Neng-yu Chen

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BACKGROUND AND PURPOSE Ifosfamide nephrotoxicity is a serious adverse effect for children undergoing cancer chemotherapy. Our recent in vitro studies have shown that the antioxidant N-acetylcysteine (NAC), which is used extensively as an antidote for paracetamol (acetaminophen) poisoning in children, protects renal tubular cells from ifosfamide-induced(More)
OBJECTIVE To investigate the chemical constituents from the aerial parts of Hyperricum monogynum. METHOD Compounds were isolated by various column chromatography and identified by spectral analysis. RESULT Ten compounds were isolated and identified as quercetin, quercitrin, hyperoside, rutin, (-)-epicatechin, 3,5-dihydroxy-1-methoxy-xanthone,(More)
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