Nelly Poulain

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The atypical hemolytic uremic syndrome (aHUS) is a paradigm of a disease, caused by overactivation of the alternative complement pathway secondary to a not well-understood trigger event. About 60 % of the patients present genetic or acquired abnormalities in the proteins of the alternative complement pathway. In 40 % of the cases the affected protein is the(More)
Non-Shiga-toxin-associated hemolytic uremic syndrome (atypical HUS) is a rare form of thrombotic microangiopathy which associates hemolytic anemia, thrombocytopenia, and acute renal failure. In 10 % of cases the disease is linked to presence of autoantibodies directed against Factor H (FH), the main plasmatic alternative complement pathway regulatory(More)
OBJECTIVE To describe postoperative complications and visual outcomes after immediately sequential bilateral cataract surgery (ISBCS) and to assess whether additional risk is incurred by operating on the fellow eye immediately following the first. ANIMALS STUDIED A retrospective review of 128 dogs (256 eyes) that underwent ISBCS in three veterinary(More)
  • M Niskanen, J-P Groby, +5 authors T Lähivaara
  • The Journal of the Acoustical Society of America
  • 2017
A method to characterize macroscopically homogeneous rigid frame porous media from impedance tube measurements by deterministic and statistical inversion is presented. Equivalent density and bulk modulus of the samples are reconstructed with the scattering matrix formalism, and are then linked to its physical parameters via the(More)
The complement system is a complex system involving serum and membrane proteins interacting in a regulated manner. The complement system plays a major role in antibacterial immunity, in inflammation, and in immune complex processing. Therefore, deficiencies in complement proteins are associated with increased susceptibility to bacterial infections and(More)
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