Nelia Aeckerle

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Mammalian spermatogenesis is maintained by spermatogonial stem cells (SSCs). However, since evidentiary assays and unequivocal markers are still missing in non-human primates (NHPs) and man, the identity of primate SSCs is unknown. In contrast, in mice, germ cell transplantation studies have functionally demonstrated the presence of SSCs. LIN28 is an(More)
Primordial germ cells (PGCs) are the embryonic progenitors of sperm and egg cells. Mammalian PGCs are thought to actively migrate from the yolk sac endoderm over long distances across the embryo to reach the somatic genital ridges. The general principles of mammalian PGC development were discovered in mice. In contrast, little is known about PGC development(More)
Oogonia are characterized by diploidy and mitotic proliferation. Human and mouse oogonia express several factors such as OCT4, which are characteristic of pluripotent cells. In human, almost all oogonia enter meiosis between weeks 9 and 22 of prenatal development or undergo mitotic arrest and subsequent elimination from the ovary. As a consequence, neonatal(More)
Frei verfügbare Informationen zur tatsächlichen Anwendung chemischer Pflanzenschutzmittel (PSM) in der Landwirtschaft werden für eine Reihe von wissenschaftlichen Fragestellungen wie auch für die politische Argumentation dringend benötigt. Deshalb werden seit dem Jahr 2000 regelmäßig Erhebungen zur Anwendung chemischer PSM in den wichtigsten(More)
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