Nele Ondreka

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BACKGROUND Understanding the pathogenesis of the chiari-like malformation in the Cavalier King Charles Spaniel (CKCS) is incomplete, and current hypotheses do not fully explain the development of syringomyelia (SM) in the spinal cords of affected dogs. This study investigates an unconventional pathogenetic theory for the development of cerebrospinal fluid(More)
Premature closure of cranial base synchondroses has been proposed as the mechanism for brachycephaly in dogs and caudal occipital malformation syndrome (COMS) in Cavalier King Charles Spaniels. The purpose of this retrospective study was to compare times of closure for cranial base synchondroses in mesaticephalic, brachycephalic, and Cavalier King Charles(More)
BACKGROUND Magnetic resonance imaging (MRI) findings of canine brains with enlarged ventricles in asymptomatic dogs were compared to those in dogs with clinically relevant internal hydrocephalus, in order to determine the imaging findings indicative of a relevant increase in intraventricular pressure. Discrimination between clinically relevant hydrocephalus(More)
Large cerebral ventricles are a frequent finding in brains of dogs with brachycephalic skull conformation, in comparison with mesaticephalic dogs. It remains unclear whether oversized ventricles represent a normal variant or a pathological condition in brachycephalic dogs. There is a distinct relationship between white matter and grey matter in the cerebrum(More)
The aim of this study was to identify skeletal variations in the lumbosacral junction (LSJ) of the German shepherd dog (GSD) compared with other large breeds. The radiographic traits of the LSJ were investigated in a group of 733 GSDs and a control group of 334 dogs of other breeds that were matched in terms of size. Nine morphological and 17 morphometric(More)
OBJECTIVE The diagnostic value of CT and MRI regarding the diagnosis of coronoid pathology in the dog. MATERIAL AND METHODS Computed tomography (CT) and magnetic resonance imaging (MRI) of the elbow joint were performed in dogs with clinical and radiological signs of coronoid pathology. Afterwards, all dogs underwent arthroscopic surgery. For the computed(More)
BACKGROUND A number of studies have attempted to quantify the relative volumes of the endocranial volume and brain parenchyma in association with the pathogenesis of the Chiari-like malformation (CLM) in the Cavalier King Charles spaniel (CKCS). In our study we examine the influence of allometric scaling of the brain and cranial cavity volume on(More)
BACKGROUND Neuropathic pain can be a clinical sign in Cavalier King Charles Spaniels (CKCS) with syringomyelia. The pathophysiology of this pain is not fully understood. HYPOTHESIS Neuropathic pain in CKCS is a result of a neuroinflammatory process. ANIMALS Twenty-six client-owned dogs: 15 dogs with clinical signs of cervical hyperesthesia (group 1),(More)
A 4-year-old, 30.6-kg castrated male mixed-breed dog was referred for evaluation of acute diarrhea, inappetence, weight loss, and lethargy. The dog had otherwise been healthy since being adopted from a Greek animal shelter 18 months before presentation. The only other household pet was its clinically healthy littermate. On examination, the dog was(More)
Our aim was to determine the relative volume of the occipital bone of Cavalier King Charles spaniels with and without syringohydromyelia and normal French bulldogs to reappraise the role of a possible insufficiency of the paraxial mesoderm in the pathogenesis of the caudal occipital malformation syndrome. Analysis of the occipital bone volume of 43 dogs(More)