Neill Miller

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The Globus Toolkit Monitoring and Discovery System (MDS4) defines and implements mechanisms for service and resource discovery and monitoring in distributed environments. MDS4 is distinguished from previous similar systems by its extensive use of interfaces and behaviors defined in the new WSResource Framework and WS-Notification specifications, and by its(More)
Methods for describing structured data are a key aid in application development. The MPI standard defines a system for creating “MPI types” at run time and using these types when passing messages, performing RMA operations, and accessing data in files. Similar capabilities are available in other middleware. Unfortunately many implementations perform poorly(More)
In production Grids for scientific applications, service and resource failures must be detected and addressed quickly. In this paper, we describe the monitoring infrastructure used by the Earth System Grid (ESG) project, a scientific collaboration that supports global climate research. ESG uses the Globus Toolkit Monitoring and Discovery System (MDS4) to(More)
The use of wide-pore silica-based hydrophilic aza-ether bonded phases for the chromatographic separation of proteins under anion-exchange conditions was studied. Polyether silanes containing terminal morpholine or piperazine derivatives are synthesized for attachment to the silica surface and provide a flexible approach to bonded phase design. In one(More)
Highly parallel applications often make use of either highly parallel file systems or large numbers of independent disks. Either of these approaches can provide high data rates necessary for parallel applications. However, the failure of a single disk or server can render the data useless. Conventional techniques, such as those based on applying erasure(More)
Petascale science is an end-to-end endeavour, involving not only the creation of massive datasets at supercomputers or experimental facilities, but the subsequent analysis of that data by a user community that may be distributed across many laboratories and universities. The new SciDAC Center for Enabling Distributed Petascale Science (CEDPS) is developing(More)
In this paper, we discuss recent development and implementation efforts by the Earth System Grid (ESG) concerning its security infrastructure. ESG's requirements are to make user logon as easy as possible and to facilitate the integration of security services and Grid components for both developers and system administrators. To meet that goal, we leverage(More)
We introduce and discuss preliminary experience with an application that has vast potential to exploit the Grid for social benefit and offers interesting resource assessment and allocation challenges, having real-time aspects: image registration. Image registration is generally formulated as an optimization problem that satisfies constraints, such as(More)
This paper is a continuation of the evaluation of hydrophilic ether columns for the separation of proteins by hydrophobic-interaction chromatography. In this approach, linear salt gradients of decreasing concentration of ammonium sulfate yield sharp chromatographic peaks with high mass recovery and maintenance of biological activity. Mild adsorption(More)