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There is increasing evidence that chronic pain problems are characterised by alterations in brain structure and function. Chronic back pain is no exception. There is a growing sentiment, with accompanying theory, that these brain changes contribute to chronic back pain, although empirical support is lacking. This paper reviews the structural and functional(More)
BACKGROUND There is currently no strong consensus regarding the optimal management of complex regional pain syndrome although a multitude of interventions have been described and are commonly used. OBJECTIVES To summarise the evidence from Cochrane and non-Cochrane systematic reviews of the effectiveness of any therapeutic intervention used to reduce(More)
OBJECTIVES To investigate impairments in sensory function in chronic non-specific low back pain patients, and the relationship between any impairment and the clinical features of the condition. DESIGN A cross-sectional case-control study. SETTING Laboratory-based study. PARTICIPANTS Nineteen chronic non-specific low back pain patients and 19 healthy(More)
We present the tail asymptotics in a queue serviced at constant rate and whose input process has long-range dependence , for example, fractional Brownian Motion (fBM) with Hurst parameter H > 1=2. Some heterogeneous su-perpositions of such sources are also treated. We examine the experimental basis for self-similar modelling. If uctu-ations in traac levels(More)
The objective of this study was to determine the effects of plane of nutrition during early and mid-pregnancy on the performance of mature ewes and their offspring. From day 0 to day 39 post mating (early pregnancy, EP), 82 multiparous ewes were fed to provide either 60% (low, L), 100% (medium, M) or 200% (high, H) of predicted metabolisable energy (ME)(More)