Neil Maredia

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BACKGROUND In patients with suspected coronary heart disease, single-photon emission computed tomography (SPECT) is the most widely used test for the assessment of myocardial ischaemia, but its diagnostic accuracy is reported to be variable and it exposes patients to ionising radiation. The aim of this study was to establish the diagnostic accuracy of a(More)
Background The prognostic importance of the ischaemic and scar burden, and their impact on coronary heart disease (CHD) patient management is well established from single photon emission computed tomography (SPECT) studies. Recently, cardiac magnetic resonance (CMR) has been shown to have superior sensitivity for the detection of CHD compared with SPECT(More)
Systemic amyloidosis commonly affects the heart. Indeed, cardiac symptoms may be the first clinical indicator of underlying amyloid deposition. Using two case studies, this article reviews the latest evidence regarding cardiac amyloidosis. The diagnosis of cardiac involvement can be established through imaging with echocardiography and magnetic resonance.(More)
BACKGROUND Several investigations are currently available to establish the diagnosis of coronary heart disease (CHD). Of these, cardiovascular magnetic resonance (CMR) offers the greatest information from a single test, allowing the assessment of myocardial function, perfusion, viability and coronary artery anatomy. However, data from large scale studies(More)
AIM To compare three-dimensional (3D) k-t sensitivity encoded (k-t SENSE) cine cardiovascular magnetic resonance (CMR), before and after contrast administration, against standard 2D imaging for the assessment of left ventricular volumes and mass. METHOD Twenty-six subjects (14 volunteers, 12 patients) underwent multiple breathhold 2D balanced turbo-field(More)
BACKGROUND Coronary artery disease is the leading cause of death in women, and underdiagnosis contributes to the high mortality. This study compared the sex-specific diagnostic performance of cardiovascular magnetic resonance (CMR) and single-photon emission computed tomography (SPECT). METHODS AND RESULTS A total of 235 women and 393 men with suspected(More)
BACKGROUND Three dimensional echo is a relatively new technique which may offer a rapid alternative for the examination of the right heart. However its role in patients with non-standard ventricular size or anatomy is unclear. This study compared volumetric measurements of the right ventricle in 25 patients with adult congenital heart disease using both(More)
OBJECTIVE Despite a significant expansion in the use of cardiac MRI (CMR), there is inadequate evaluation of its incremental impact on clinical decision-making over and above other well-established modalities. We sought to determine the incremental utility of CMR in routine practice. METHODS 629 consecutive CMR studies referred by 44 clinicians from 9(More)
Background Diagnosis of coronary ischemia by perfusion CMR has high sensitivity and specificity when using X-ray coronary angiography as the reference standard. A variety of possible reasons have been given for false negative perfusion CMR studies, such as suboptimal image quality, technical reasons, or the potential discrepancy between angiographic(More)
PURPOSE To assess the reproducibility of semiquantitative and quantitative analysis of first-pass myocardial perfusion cardiovascular magnetic resonance (CMR) in healthy volunteers. MATERIALS AND METHODS Eleven volunteers underwent myocardial perfusion CMR during adenosine stress and rest on 2 separate days. Perfusion data were acquired in a single(More)