Neil C. Stickland

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Obesity is generally associated with high intake of junk foods rich in energy, fat, sugar and salt combined with a dysfunctional control of appetite and lack of exercise. There is some evidence to suggest that appetite and body mass can be influenced by maternal food intake during the fetal and suckling life of an individual. However, the influence of a(More)
In the pig, undernutrition in utero causes low birth weight, a decrease in muscle fiber number, and a reduction in postnatal growth rate. The effect on fiber number is mediated via a reduced secondary fiber population. Within a litter of pigs, lighter-weight pigs have probably suffered some deficit in muscle fiber number. In an attempt to improve the number(More)
The largest and smallest littermates were chosen by weight from litters of 38 days' gestation to 1 day post partum. Complete frozen sections of the semitendinosus muscle were used to provide a qualitative and quantitative account of the development of the primary and secondary generations of muscle fibres. The results showed that the time of formation of(More)
From fertilisation to hatching one group of salmon embryos was reared at ambient temperatures (fluctuating around 1.6° C) and another at 10° C. At Gorodilov stages 28, 30 and 33 transverse sections of whole embryos were obtained for light and electron microscopy. Total cross-sectional areas, fibre numbers, fibre diameters and myofibrillar areas of the white(More)
1. The effect of manipulating egg incubation temperature for short periods on turkey muscle development was determined using the M. semitendinosus, a thigh muscle, as the model. 2. Experiment 1. Eggs were incubated at a control temperature of 37.5 degrees C. For a 4-d period of 0 to 4, 5 to 8, 9 to 12, 13 to 16, 17 to 20 or 21 to 24 embryonic days (ED) eggs(More)
The growth of red and white muscle was investigated in the rainbow trout, using fish from 2.2 cm to 71 cm in length. In the white muscle, fibre hyperplasia, initially, accounted for all muscle growth but its relative contribution decreased as the contribution from fibre hypertrophy increased. At and above about 65 cm there was no hyperplasia, and this(More)
Fast-growing strains of pigs and of other animals tend to have more muscle fibers than do slow-growing strains. The relationship between fiber number and growth rate was extended by examining pigs within the same strain. Seven litters of pigs (n = 66) were weighted at monthly intervals from birth to approximately 80 kg. The semitendinosus muscle was removed(More)
The chick embryo, developing in the egg, is an ideal system in which to investigate the effects of incubation environment on the development of the embryo. We show that raising the temperature of the eggs by just one degree, from 37.5 degrees C to 38.5 degrees C, during embryonic days (ED) 4-7 causes profound changes in development. We demonstrate that(More)
We have shown previously that a maternal junk food diet during pregnancy and lactation plays a role in predisposing offspring to obesity. Here we show that rat offspring born to mothers fed the same junk food diet rich in fat, sugar and salt develop exacerbated adiposity accompanied by raised circulating glucose, insulin, triglyceride and/or cholesterol by(More)
Biochemical and histological analyses were used to study the number and size of cells (cellularity) in tissues of fast-growing, genetically modified Arctic char (Salvelinus alpinus L.), overexpressing sockeye salmon (Oncorhynchus nerka) growth hormone gene (OnGH1). DNA contents of muscle, heart, and liver were compared in transformed, sibling (age control)(More)