Neil B. Friedman

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BACKGROUND The presence of tumor cells at the margins of breast lumpectomy specimens is associated with an increased risk of ipsilateral tumor recurrence. Twenty to 30 % of patients undergoing breast-conserving surgery require second procedures to achieve negative margins. This study evaluated the adjunctive use of the MarginProbe device (Dune Medical(More)
The authors report the successful conservative treatment of a tuboovarian abscess in a 25-year old woman who presented with low grade fever and severe right sciatic pain. Computed tomography and ultrasonography corroborated a clinical diagnosis of tuboovarian abscess after an initial diagnosis of epidural abscess had been made. This is the first report of a(More)
Standard axial CT supplemented by two-dimensional reconstruction in coronal, sagittal, and oblique planes was used to evaluate 35 patients with a history of breast cancer and clinical symptoms suggestive of brachial plexopathy. In five patients, definite tumor recurrence was seen either within the axilla or the neurovascular bundle or near the origin of the(More)
With the extended indications for abdominal and pelvic radiation therapy, administered at higher dosage levels, an increased incidence of radiation injury to the intestine can be anticipated. Increased efforts are urgently needed to develop innovative methods in the detection, prevention, and management of radiation-induced intestinal injury. Fifty cases of(More)
Single-dose intraoperative radiotherapy (IORT) is an emerging treatment for women with early stage breast cancer. The objective of this study was to define the frequency of IORT use, patient selection, and outcomes of patients treated in North America. A multi-institutional retrospective registry was created, and 19 institutions using low-kilovoltage IORT(More)