Learn More
Recent advances in the understanding of the pathophysiological mechanisms underlying Alzheimer's disease and other cognitive deficits have pointed to novel strategies for drug development. Animal models have contributed noticeably to these advances and are an indispensible part in the evaluation of therapeutics. This review is an exhaustive study of animal(More)
A huge body evidences suggest that obesity is the single great risk factor for the development of dementia. Recently, silymarin, a flavonoid, clinically in use as a hepatoprotectant, has been reported to prevent amyloid beta-induced memory impairment by reducing oxidative stress and inflammation in mice brain. However, its potential in high-fat-diet(More)
Many studies report that heavy metals such as aluminum are involved in amyloid beta aggregation and neurotoxicity. Further, high concentration of aluminum in the brain deregulates calcium signaling which contributes to synaptic dysfunction and halts neuronal communication which ultimately leads to the development of Alzheimer’s disease. Recently, diltiazem,(More)
I) Effect of heavy metals on Autoimmune diseases II) Immunomodulatory and anti-inflammatory effect of herbal medicines and natural plant products on autoimmune diseases 3.Projects completed: I) A comparative study of new unani formulation with Majoon Suranjan against experimental arthritis II) Studies on anti-arthritic potential of Zingiber officinalis in(More)
  • 1