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Recent advances in the understanding of the pathophysiological mechanisms underlying Alzheimer's disease and other cognitive deficits have pointed to novel strategies for drug development. Animal models have contributed noticeably to these advances and are an indispensible part in the evaluation of therapeutics. This review is an exhaustive study of animal(More)
A huge body evidences suggest that obesity is the single great risk factor for the development of dementia. Recently, silymarin, a flavonoid, clinically in use as a hepatoprotectant, has been reported to prevent amyloid beta-induced memory impairment by reducing oxidative stress and inflammation in mice brain. However, its potential in high-fat-diet(More)
Many studies report that heavy metals such as aluminum are involved in amyloid beta aggregation and neurotoxicity. Further, high concentration of aluminum in the brain deregulates calcium signaling which contributes to synaptic dysfunction and halts neuronal communication which ultimately leads to the development of Alzheimer’s disease. Recently, diltiazem,(More)
INTRODUCTION Sella turcica is an important cephalometric structure and attempts have been made in the past to correlate its dimensions to the malocclusion. However, no study has so far compared the size of sella to the jaw bases that determine the type of malocclusion. The present study was undertaken to find out any such correlation if it exists. (More)
Anxiety is a term used to describe uncomfortable feelings of nervousness, worry, and tension, which we all feel from time to time. Bouras, and Holt (2007) Anxiety is often accompanied by muscular tension. American Psychiatric Association (2013) Anxiety is a feeling of fear, worry, and uneasiness, usually generalized and unfocused as an overreaction to a(More)
  • A Yandong Mao, T Robert, Morris, Chu0efn Omiwfr, Yandong Mao, Alex Austin +18 others
  • 2015
This dissertation addresses two challenges relating to in-memory storage systems. The first challenge is storing and retrieving data at a rate close to the capabilities of the underlying memory system, particularly in the face of parallel accesses from multiple cores. We present Masstree, a high performance in-memory key-value store that runs on a single(More)
Energy is the main constraint in wireless sensor network. Hence to increase the lifetime of WSN, the requirement is to have an energy efficient routing protocol .For this purpose the hierarchical routing architecture is used wherein the whole network is divided into group of clusters and only cluster head is responsible for forwarding the data to base(More)
  • Neha, Mrs Rainu Nandal
  • 2015
Wireless Sensor Network is a resource constraint network, in which all sensor nodes have limited resources. In order to save resources and energy data must be aggregated to reduce the amount of traffic in the network. Data aggregation has to done with the help of clustering scheme. Clusters reduce the localized traffic by means of grouping sensor nodes and(More)