Neda Savic

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The nucleoplasmin family of histone chaperones is identified by a pentamer-forming domain and multiple acidic tracts that mediate histone binding and chaperone activity. Within this family, a novel domain organization was recently discovered that consists of an N-terminal nucleoplasmin-like (NPL) domain and a C-terminal FKBP peptidyl-proline isomerase(More)
In order to reproduce, all cells must duplicate their genomes accurately. Active replication forks encounter impediments such as DNA adducts, strand breaks, bound proteins, or secondary DNA structures that impair their ability to duplicate the DNA. UV-irradiation causes DNA damage that arrests replication forks and induces distinct intermediates during the(More)
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