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Refocused steady-state free precession (SSFP) is limited by its high sensitivity to local field variation, particularly at high field strengths or the long repetition times (TRs) necessary for high resolution. Several methods have been proposed to reduce SSFP banding artifact by combining multiple phase-cycled SSFP acquisitions, each differing in how(More)
Medical imaging has enormous potential for early disease prediction, but is impeded by the difficulty and expense of acquiring data sets before symptom onset. UK Biobank aims to address this problem directly by acquiring high-quality, consistently acquired imaging data from 100,000 predominantly healthy participants, with health outcomes being tracked over(More)
PURPOSE To deploy and quantify the accuracy of 3D dual echo steady state (DESS) MR arthrography with hip traction to image acetabular cartilage. Clinical magnetic resonance imaging (MRI) sequences used to image hip cartilage often have reduced out-of-plane resolution and may lack adequate signal-to-noise to image cartilage. MATERIALS AND METHODS Saline(More)
PURPOSE To compare signal-to-noise ratios (SNRs) and T*(2) maps at 3 T and 7 T using 3D cones from in vivo sodium images of the human knee. MATERIALS AND METHODS Sodium concentration has been shown to correlate with glycosaminoglycan content of cartilage and is a possible biomarker of osteoarthritis. Using a 3D cones trajectory, 17 subjects were scanned(More)
OBJECTIVE MRI is the most accurate noninvasive method available to diagnose disorders of articular cartilage. Conventional 2D and 3D approaches show changes in cartilage morphology. Faster 3D imaging methods with isotropic resolution can be reformatted into arbitrary planes for improved detection and visualization of pathology. Unique contrast mechanisms(More)
Flow-independent angiography is a non-contrast-enhanced technique that can generate vessel contrast even with reduced blood flow in the lower extremities. A method is presented for producing these angiograms with magnetization-prepared balanced steady-state free precession (bSSFP). Because bSSFP yields bright fat signal, robust fat suppression is essential(More)
Balanced steady-state free precession (SSFP) is hindered by the inherent off-resonance sensitivity and unwanted bright fat signal. Multiple-acquisition SSFP combination methods, where multiple datasets with different fixed RF phase increments are acquired, have been used for shaping the SSFP spectrum to solve both problems. We present a new combination(More)
Sodium magnetic resonance imaging (MRI), or imaging of the 23Na nucleus, has been under exploration for several decades, and holds promise for potentially revealing additional biochemical information about the health of tissues that cannot currently be obtained from conventional hydrogen (or proton) MRI. This additional information could serve as an(More)
PURPOSE The objective of this study was to determine whether a sodium phased array would improve sodium breast MRI at 3 T. The secondary objective was to create acceptable proton images with the sodium phased array in place. METHODS A novel composite array for combined proton/sodium 3 T breast MRI is compared with a coil with a single proton and sodium(More)
Quantitative sodium MRI requires accurate knowledge of factors affecting the sodium signal. One important determinant of sodium signal level is the transmit B(1) field strength. However, the low signal-to-noise ratio typical of sodium MRI makes accurate B(1) mapping in reasonable scan times challenging. A new phase-sensitive B(1) mapping technique has(More)