Arg126 and Asp49 Are Essential for the Catalytic Function of Microsomal Prostaglandin E2 Synthase 1 and Ser127 Is NotJoan Raouf, Nazmi Rafique, +6 authors Linda SpahiuPloS one2016INTRODUCTION Prostaglandins are signaling molecules that regulate different physiological processes, involving allergic and inflammatory responses and cardiovascular control. They are involved in… (More)