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A comparative study between nanoparticle-targeted therapeutics and bioconjugates as obesity medication.
TLDR
The systemic injection of DIO mice with a low dose of KLA-PTNP resulted in a reduction in body weight, as evidenced by a significant decrease in serum leptin levels, in parallel with an antiobesity effect on dysfunctional adipose cells, including adipocytes and macrophages. Expand
Transcytosis-Targeting Peptide: A Conductor of Liposomal Nanoparticles through the Endothelial Cell Barrier.
TLDR
The in vivo endothelial penetration of liposomes in adipose tissue is conferred by the dual modification of the particles with TTP and tissue-targeting ligands, and this technology promises innovations in intravenously available delivery system to tissue parenchyma. Expand
Non-Fickian Transport of Pioglitazone from a CMC/PVA/SDS Blend Patch Gel
Drugs having narrow absorption window in GIT like pioglitazone has poor absorption and needs alternative route to be delivered. In order to introduce transdermal applicability of pioglitazone here weExpand