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Diabetic neuropathy is a heterogeneous group of disorders with extremely complex pathophysiology and affects both somatic and autonomic components of the nervous system. Neuropathy is the most common chronic complication of diabetes mellitus. Metabolic disruptions in the peripheral nervous system, including altered protein kinase C activity, and increased(More)
The embryo sac (female gametophyte) plays an important role in double fertilization. The female gametophyte is composed of four specific cell types: the synergids that attract pollen tubes, the egg cell and central cell which are fusion partners for the two sperm cells, and the antipodal cells whose function is unknown. As a resource for gene discovery and(More)
BACKGROUND According to the World Health Organization, probiotics are live microorganisms which when administered in adequate amounts and confer a health benefit to the host. Use of probiotics in children to improve oral health may lead to non-pathogenic bacteria replacing cariogenic bacteria. Dairy foods like cheese, curd, and milk are considered useful(More)
ETHNOPHARMACOLOGICAL RELEVANCE Long term hyperglycemia leads to development of complications associated with diabetes. Diabetic complications are now a global health problem without effective therapeutic approach. Hyperglycemia and oxidative stress are important components for the development of diabetic complications. Over the past few decades, herbal(More)
In certain regions of the United States in which organ donor shortages are persistent and competition is high, recipients wait longer and are critically ill with Model for End-Stage Liver Disease (MELD) scores ≥40 when they undergo liver transplantation. Recent implementation of Share 35 has increased the percentage of recipients transplanted at these(More)
  • Amritpal Singh, Sanjiv Duggal, Navpreet Kaur, Jaswinder Singh
  • 2009
Berberine is an isoquinoline alkaloid, present in roots and stem-bark of Berberis species. Berberine based formulations, are widely used in traditional systems of medicine including, Ayurveda and Traditional Chinese Medicine. Berberine has demonstrated wide range of pharmacological activities including; antihypertensive, anti-inflammatory, antioxidant,(More)
The intracellular enzyme dihydrodipicolinate synthase (DHDPS, E.C. from Pseudomonas aeruginosa is a potential drug target because it is essential for the growth of bacteria while it is absent in humans. Therefore, in order to design new compounds using structure based approach for inhibiting the function of DHDPS from P. aeruginosa (Ps), we have(More)
The direct-acting antivirals (DAAs) constitute an emerging group of small molecule inhibitors that effectively treat hepatitis C virus (HCV) infection, a common comorbidity in end-stage renal disease patients. To date, there are no data to guide use of these agents in kidney transplant patients. The authors collected data from 20 consecutive kidney(More)
The superficial and deep body temperatures of 40 healthy females undergoing total abdominal hysterectomy were measured during surgery and for 4 h afterwards. The patients were allocated randomly to one of five groups and anaesthetized to produce an end-tidal concentration of 1% halothane, 1% enflurane, 2% enflurane, 1% isoflurane or 2% isoflurane. The(More)
BACKGROUND Posttransplant lymphoproliferation is most often observed in pediatric transplant recipients who experience primary Epstein-Barr virus (EBV) infection at the time of or after transplantation. Lymphoproliferation is believed to be caused by impaired control of EBV-infected cells, which may be of recipient or donor origin. Most studies of EBV(More)