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Tubulointerstitial fibrosis is a hallmark feature of chronic renal injury. Specific therapies to control the progression of renal fibrosis toward end-stage renal failure are limited. Previous studies have demonstrated that expression of endogenous bone morphogenic protein-7 (BMP-7) is reduced in the kidneys of several inducible mouse models of acute and(More)
The Routing Protocol available in present generation of MANET focuses mainly on the performance and only a little capability against the malicious attacks. The foremost concerned security issue in MANET is to protect the network layer from malicious attacks, thereby identifying and preventing malicious nodes. The selection of optimal path for routing and(More)
Bladder cancer (predominantly transitional cell) is the fourth leading cause of cancer in males and the ninth in females. The American Cancer Society estimates nearly 68,000 new cases with 14,000 deaths this year [1]. Metastatic spread is lymphangitic or hematogenous, and common sites affected are regional lymph nodes, liver, lung, and bone [2]. The(More)
Nitric oxide (NO) and salicylic acid (SA) are important signaling molecules in plant system. In the present study both NO and SA showed a protective role against arsenite (AsIII) stress in rice plants when supplied exogenously. The application of NO and SA alleviated the negative impact of AsIII on plant growth. Nitric oxide supplementation to AsIII treated(More)
Genetic polymorphisms in diagnostic antigens are important factors responsible for variable performance of rapid diagnostic tests. Additionally, the failure of antigen expression due to gene deletion may also contribute to variable performance. We report Indian Plasmodium falciparum field isolates lacking both Pfhrp2 and Pfhrp3 genes leading to false(More)
YLR162W is an uncharacterized Saccharomyces cerevisiae ORF whose transcript level is elevated in cells under environmental stress, during α-factor response and in stationary phase. We obtained a partial cDNA clone of YLR162W by subtractive hybridization cloning of genes that were not expressed in a CoCl2 resistant DNA synthesis mutant but expressed in its(More)
Rapid diagnostic tests (RDTs) have revolutionized the diagnosis of malaria. Among the various factors affecting RDTs sensitivity is genetic variation of the antigen used. The genetic variation in PfHRP2 and PfHRP3 proteins was studied among the Indian Plasmodium falciparum isolates. One hundred and forty isolates of P. falciparum were collected from six(More)
The use of antimalarial drugs in India has evolved since the introduction of quinine in the 17 th century. Since the formal establishment of a malaria control programme in 1953, shortly after independence, treatments provided by the public sector ranged from chloroquine, the mainstay drug for many decades, to the newer, recently introduced artemisinin based(More)
Salmonella enterica subsp. arizonae is a common gut inhabitant of reptiles, with snakes as the most common reservoir. Though human cases due to this organism are exceedingly rare, it may infect young infants and immunocompromised individuals with a history of intimate associations with reptiles. Gastroenteritis is the most common presentation; others(More)