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Synthesis, DNA interaction and anticancer activity of 2-anthryl substituted benzimidazole derivatives
2-Anthryl benzimidazole derivatives (5–7) with hydrogen, carboxyl and benzoyl substituents at the 5th position have been synthesized using a silica supported periodic acid catalyst. The DNA cleavageExpand
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Iso-energetic multiple conformations of hypermodified nucleic acid base wybutine (yW) which occur at 37(th) position in anticodon loop of tRNA(Phe).
Conformational preferences of wybutine (yW) have been studied by quantum chemical semi-empirical Perturbative Configuration Interaction with Localized Orbitals (PCILO) and PM3 methods. Automated fullExpand
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Conformational Preferences of Modified Nucleoside N2-methylguanosine (m2G) and Its Derivative N2, N2-dimethylguanosine (m22G) Occur at 26th Position (Hinge Region) in tRNA
Conformational preferences of the modified nucleosides N2-methylguanosine (m2G) and N2, N2-dimethylguanosine (m22G) have been studied theoretically by using quantum chemical perturbativeExpand
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Structural significance of hypermodified nucleic acid base hydroxywybutine (OHyW) which occur at 37th position in the anticodon loop of yeast tRNA(Phe).
Conformational preferences of hypermodified nucleic acid base hydroxywybutine (OHyW) have been studied using quantum chemical single point semi-empirical PM3 method. Automated geometry optimizationExpand
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Structural significance of modified nucleosides k2C and t6A present in the anticodon loop of tRNAIle
The structural significance of the hypermodified nucleosides lysidine (k2C) and N6-(N-threonylcarbonyl) adenosine (t6A) present in the anticodon loop of E. coli tRNAIle has not been studied in detailExpand
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QUANTUM CHEMICAL STUDY TO INVESTIGATE THE EFFECTS OF 5′-3′ DIPHOSPHATE BACKBONE ON THE CONFORMATION OF HYPERMODIFIED NUCLEOTIDE LYSIDINE (K2C) OCCUR AT WOBBLE (34TH) POSITION IN THE ANTICODON LOOP OF
Conformational preferences of hypermodified nucleotide ‘lysidine’ in the model diphosphate (Me-p-k2Cp-Me) segment of anticodon loop of tRNAIle have been studied by using quantum chemical perturbativeExpand
Finite Element Modelling and Analysis of Contact Stiffness of Workpiece Fixture System
The fixture design and analysis lead-time is always a major influencing factor for the bottleneck between product design and manufacturing. With advent analysis and simulation tools, there is a lotExpand
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