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OBJECTIVE A randomized, parallel-group, open-label, multicenter 16-week clinical trial compared efficacy and safety of repaglinide monotherapy and nateglinide monotherapy in type 2 diabetic patients previously treated with diet and exercise. RESEARCH DESIGN AND METHODS Enrolled patients (n = 150) had received treatment with diet and exercise in the(More)
OBJECTIVE To identify factors associated with growth in children on growth hormone (GH) therapy using data from the American Norditropin Studies: Web-enabled Research (ANSWER) Program® registry. METHODS GH-naïve children with GH deficiency, multiple pituitary hormone deficiency, idiopathic short stature, Turner syndrome, or a history of small for(More)
In longitudinal clinical trials, missing data are mostly related to dropouts. Some dropouts appear completely at random. The source for other dropouts is withdrawal from trials due to lack of efficacy. For the latter case, the analyses of the actual observed data and completers can produce bias. One of the approaches to comply with the intent-to-treat(More)
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