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Tissue engineering is essentially a technique for imitating nature. Natural tissues consist of three components: cells, signalling systems (e.g. growth factors) and extracellular matrix (ECM). The ECM forms a scaffold for its cells. Hence, the engineered tissue construct is an artificial scaffold populated with living cells and signalling molecules. A huge(More)
OBJECTIVE Investigate the 2D/3D geometry of femoral curvature and femoral length using the advanced technique of computerized tomography combined with reverse engineering techniques. MATERIAL AND METHOD The present study was performed using reverse engineering technique based on CT data of 99 cadaveric femora. The femur was divided into three segments,(More)
Tissue engineering scaffold is a biological substitute that aims to restore, to maintain, or to improve tissue functions. Currently available manufacturing technology, that is, additive manufacturing is essentially applied to fabricate the scaffold according to the predefined computer aided design (CAD) model. To develop scaffold CAD libraries, the(More)
OBJECTIVE To study the stress distributions in normal and osteoarthritic knee joints using the finite element method (FEM). MATERIAL AND METHOD Three normal and three varus knee joints are included in the study. Computed tomography (CT) images of the lower extremities are used to create 3D geometric models consisting of bones, articular cartilages,(More)
PURPOSE To present a rapid-prototype (RP) endoprosthesis replacement after tumor resection in patients with bone metastasis of the upper extremity. The short-term complications and functional outcomes were evaluated as well as the survival of patients and endoprosthesis. METHODS Bone metastasis patients who required bone resection and endoprosthesis(More)
PURPOSE The biomechanical performance of a novel engineered porous-structure implant (EPSI) with various porosities and a conventional solid-structure implant (CSSI) was investigated and compared. MATERIALS AND METHODS The three-dimensional finite element method was applied to titanium dental implant models placed in a block of bone that included both(More)
This paper proposes a novel method of using an antero-posterior buttress screw at the distal fragment just below the fracture site in conjunction with the sliding hip screw (SHS) to resist excessive femoral medialisation. A virtual assessment of the effectiveness of this new method was performed using the finite element analysis. The results indicate that(More)
PURPOSE To assess morphological parameters of proximal femur and acetabulum in Thai population with three-dimensional measurement technique, and to analysis of collateral side symmetric, gender difference, and correlation between morphometric parameters. METHODS Investigation was performed in 240 femurs. All three-dimensional femur models were acquitted(More)
The geometric mismatch analysis of the retrograde nail was performed in 108 Asian cadaveric adult femora. The insertion was done virtually based on a three-dimensional geometric model derived from computed tomographic images. The investigation was performed at eight levels located at 120, 140, 160, 180, 200, 220 and 240 mm above the condylar surface. The(More)
OBJECTIVE To investigate the optimal entry point for retrograde femoral nailing using medical imaging and reverse engineering technologies. MATERIAL AND METHOD One hundred and eight adult cadaveric femurs were scanned using a computed tomography (CT) scanner. To obtain three-dimensional models, medical imaging and reverse engineering technologies were(More)