Nathan L. Dykes

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483 H ip dysplasia in dogs is a polygenic disease characterized by hip instability that results in secondary osteoarthritis, lameness, and physical disability. 1 Medical and surgical management of the condition have economic and emotional impacts on dog owners and breeders. As a complex trait, HD is caused by genetic and environmental factors that influence(More)
Canine hip dysplasia is a common developmental inherited trait characterized by hip laxity, subluxation or incongruity of the femoral head and acetabulum in affected hips. The inheritance pattern is complex and the mutations contributing to trait expression are unknown. In the study reported here, 240 microsatellite markers distributed in 38 autosomes and(More)
BACKGROUND Canine hip dysplasia (HD) is a common polygenic trait characterized by hip malformation that results in osteoarthritis (OA). The condition in dogs is very similar to developmental dysplasia of the human hip which also leads to OA. METHODOLOGY/PRINCIPAL FINDINGS A total of 721 dogs, including both an association and linkage population, were(More)
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