Nathan Heinze

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The rod of sarcomeric myosins directs thick filament assembly and is characterized by the insertion of four skip residues that introduce discontinuities in the coiled-coil heptad repeats. We report here that the regions surrounding the first three skip residues share high structural similarity despite their low sequence homology. Near each of these skip(More)
This paper presents the results of a six-year longitudinal survey of the web sites of S&P 500 companies. Using nine design and functional measures developed based on prior research, we find that S&P 500 companies have experienced significant transformation of their web presence, signified by the increasing levels of information and interactivity. We find a(More)
Sarcomeric myosins have the remarkable ability to form regular bipolar thick filaments that, together with actin thin filaments, constitute the fundamental contractile unit of skeletal and cardiac muscle. This has been established for over 50 years and yet a molecular model for the thick filament has not been attained. In part this is due to the lack of a(More)
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