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A double-blind, multicenter study compared the safety and efficacy of oral betaxolol 10 to 40 mg once daily (n = 68) with propranolol 40 to 160 mg twice daily (n = 73) in the treatment of mild to moderate essential hypertension. Both agents produced significant (P less than 0.01) and comparable reductions in mean supine systolic and diastolic blood(More)
This multicentre, double-blind, parallel-group, placebo-controlled study compared the antihypertensive effects of equal doses of two long-acting angiotensin converting enzyme (ACE) inhibitors. After a two-week, placebo run-in phase, 110 patients with mild to moderate hypertension were randomised to receive 10 mg lisinopril or enalapril, or placebo for 4(More)
The Netherlands Organisation for Scientific Research (NWO) and the newspaper NRC Handelsblad have organized NWO | Huygens Lectures since 1992. The lectures providing the publice at large a unique opportunity to listen to and meet famous scientists. The city council of The Hague acts as a host. (NIOB-KNAW). She is an highly appreciated spokesperson on human(More)