Nathan Anthony Mark Estes

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BACKGROUND This trial was designed to determine whether cardiac-resynchronization therapy (CRT) with biventricular pacing would reduce the risk of death or heart-failure events in patients with mild cardiac symptoms, a reduced ejection fraction, and a wide QRS complex. METHODS During a 4.5-year period, we enrolled and followed 1820 patients with ischemic(More)
This guideline contains hyperlinks to recommendations and supporting text that have been updated by the “2011 ACCF/AHA/HRS Focused Update on the Management of Patients With Atrial Fibrillation (Updating the 2006 Guideline)” (Circulation. 2011;123:104–123; doi:10.1161/CIR.0b013e3181fa3cf4) and the “2011 ACCF/AHA/HRS Focused Update on the Management of(More)
BACKGROUND Patients with nonischemic dilated cardiomyopathy are at substantial risk for sudden death from cardiac causes. However, the value of prophylactic implantation of an implantable cardioverter-defibrillator (ICD) to prevent sudden death in such patients is unknown. METHODS We enrolled 458 patients with nonischemic dilated cardiomyopathy, a left(More)
BACKGROUND Dual-chamber (atrioventricular) and single-chamber (ventricular) pacing are alternative treatment approaches for sinus-node dysfunction that causes clinically significant bradycardia. However, it is unknown which type of pacing results in the better outcome. METHODS We randomly assigned a total of 2010 patients with sinus-node dysfunction to(More)
Andrew E. Epstein, MD, FACC, FAHA, FHRS, Chair*; John P. DiMarco, MD, PhD, FACC, FAHA, FHRS*; Kenneth A. Ellenbogen, MD, FACC, FAHA, FHRS*; N. A. Mark Estes, III, MD, FACC, FAHA, FHRS; Roger A. Freedman, MD, FACC, FHRS*; Leonard S. Gettes, MD, FACC, FAHA; A. Marc Gillinov, MD, FACC, FAHA*†; Gabriel Gregoratos, MD, FACC, FAHA; Stephen C. Hammill, MD, FACC,(More)
BACKGROUND Arrhythmogenic right ventricular cardiomyopathy/dysplasia (ARVC/D) is a condition associated with the risk of sudden death (SD). METHODS AND RESULTS We conducted a multicenter study of the impact of the implantable cardioverter-defibrillator (ICD) for prevention of SD in 132 patients (93 males and 39 females, age 40+/-15 years) with ARVC/D.(More)
BACKGROUND Standard clinical practice permits the use of either single-chamber ventricular pacemakers or dual-chamber pacemakers for most patients who require cardiac pacing. Ventricular pacemakers are less expensive, but dual-chamber pacemakers are believed to be more physiologic. However, it is not known whether either type of pacemaker results in(More)
Despite improvements in cardiovascular implantable electronic device (CIED) design, application of timely infection control practices, and administration of antibiotic prophylaxis at the time of device placement, CIED infections continue to occur and can be life-threatening. This has prompted the study of all aspects of CIED infections. Recognizing the(More)