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Rapid SNP Discovery and Genetic Mapping Using Sequenced RAD Markers
Single nucleotide polymorphism (SNP) discovery and genotyping are essential to genetic mapping. There remains a need for a simple, inexpensive platform that allows high-density SNP discovery andExpand
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Induction of the Heat Shock Pathway during Hypoxia Requires Regulation of Heat Shock Factor by Hypoxia-inducible Factor-1*
Activation of heat shock proteins (Hsps) is critical to adaptation to low oxygen levels (hypoxia) and for enduring the oxidative stress of reoxygenation. Hsps are known to be regulated by heat shockExpand
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HSF-1–mediated cytoskeletal integrity determines thermotolerance and life span
The conserved heat shock transcription factor–1 (HSF-1) is essential to cellular stress resistance and life-span determination. The canonical function of HSF-1 is to regulate a network of genesExpand
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Heterotypic Signals from Neural HSF-1 Separate Thermotolerance from Longevity.
Integrating stress responses across tissues is essential for the survival of multicellular organisms. The metazoan nervous system can sense protein-misfolding stress arising in different subcellularExpand
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Integrin-linked kinase modulates longevity and thermotolerance in C. elegans through neuronal control of HSF-1
Integrin‐signaling complexes play important roles in cytoskeletal organization and cell adhesion in many species. Components of the integrin‐signaling complex have been linked to aging in bothExpand
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Hypoxic gene regulation and high-throughput genetic mapping
xi, 52 p. ; ill. (some col.) A print copy of this title is available through the UO Libraries under the call number: SCIENCE QH445.2 .B35 2008