Nathalie van der Velde

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The association of vitamin D status with bone mineral density (BMD) and Quantitative Ultrasound measurements (QUS) has been inconsistent in previous studies, probably caused by moderating effects. This study explored (1) the association of vitamin D status with QUS and BMD, and (2) whether these associations were modified by body mass index (BMI), age,(More)
This study, on the association between vitamin D status and physical performance and its decline, shows that vitamin D status is associated with physical performance in several older age groups. However, vitamin D status does not predict a decline in physical performance in individuals aged 55–65 years. Previous research in the Longitudinal Aging Study(More)
Objective The objective of this study is to investigate the association between CYP2D6*4, CYP3A5*3 and ABCB1 3435T polymorphisms and drug-related falls. Method Multivariate logistic regression was performed in an existing database in order to study the association between falls history and CYP2D6*4, CYP3A5*3, ABCB1 3435T polymorphisms in patients using(More)
We determined adherence to nine fall-related ACOVE quality indicators to investigate the quality of management of falls in the elderly population by general practitioners in the Netherlands. Our findings demonstrate overall low adherence to these indicators, possibly indicating insufficiency in the quality of fall management. Most indicators showed a(More)
Hou-Feng Zheng 1,2 *, Vincenzo Forgetta *, Yi-Hsiang Hsu *, Karol Estrada *, Alberto Rosello-Diez *, Paul J Leo *, Chitra L Dahia *, Kyung Hyun Park-Min*, Jonathan H Tobias *, Charles Kooperberg *, Aaron Kleinman, Unnur Styrkarsdottir, Ching-Ti Liu , Charlotta Uggla , Daniel S Evans , Carrie M Nielson , Klaudia Walter , Ulrika Pettersson-Kymmer , Shane(More)
Importance: Fall incidents represent a public health problem in aging societies worldwide. A major risk factor for falls is the use of fall-risk increasing drugs (FRIDs). Objectives: To investigate the effect of withdrawal of FRIDs versus ‘care as usual’ on reducing falls in community-dwelling older men and women. Design: Randomized multicenter trial.(More)
Several studies have observed positive associations between bone disease and cardiovascular disease. A potential common pathway is hyperhomocysteinemia; however, to date, there is a lack of data regarding hyperhomocysteinemic populations. Therefore, we examined both cross-sectionally and longitudinally, whether there is an association between bone(More)
Background: Vitamin D deficiency is considered a key contributor to impaired physical performance. However, many studies demonstrating this relationship were conducted in female-only populations, and recent studies investigating men specifically found no association. Nevertheless, evidence regarding an underlying gender-specific mechanism is lacking.(More)
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