Nathalie Vikulova

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It has been shown that isolated sub-epicardial (EPI) and sub-endocardial (ENDO) myocytes have distinct electrical and mechanical properties in normal heart ventricle and differently respond to interventions. We utilized our electromechanical models of EPI and ENDO myocytes to simulate their responses to the acute ischemia and to predict effects of cell(More)
Cardiac arrhythmias and long QT syndrome may be associated with increased sodium currents. Possible effects of enhanced function of sodium channels on the transmural gradient in the electrical and mechanical properties of myocardium have not been sufficiently studied. We used our cellular mathematical models to investigate effects of an increased late(More)
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