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BACKGROUND The underreporting of adverse drug reactions (ADRs) through traditional reporting channels is a limitation in the efficiency of the current pharmacovigilance system. Patients' experiences with drugs that they report on social media represent a new source of data that may have some value in postmarketing safety surveillance. OBJECTIVE A scoping(More)
BACKGROUND Bronchial asthma is the most frequent chronic respiratory disease in both adults and children. The prevalence and burden of asthma vary considerably between different regions of the world. Information on asthma in Africa is fragmentary and relatively old. OBJECTIVE The objective of this cross-sectional epidemiological survey was to determine(More)
BACKGROUND In Europe, administration of an inhaled corticosteroid (ICS) combined with a long-acting β2 agonist is approved in chronic obstructive pulmonary disease (COPD) patients with a pre-bronchodilator FEV1 < 60% predicted normal, a history of repeated exacerbations, and who have significant symptoms despite regular bronchodilator therapy. Minimal data(More)
OBJECTIVES The DUO study sought to identify the factors determining diagnostic and treatment strategies for benign prostatic hyperplasia (BPH) in daily practice. METHODS Observational study conducted in France (from June 2004 through March 2005) among a representative sample of French urologists. RESULTS Two hundred two urologists included 1027 BPH(More)
BACKGROUND The goal of asthma management is to achieve disease control, defined. as the ability to lead a normal life with normal pulmonary function. However, many epidemiological surveys have demonstrated that asthma control is unacceptable in the majority of patients. OBJECTIVE To evaluate asthma control in 624 adults with asthma in the Maghreb,(More)
The objective of this study is to determine whether spontaneous complaints about sleep or the legs could be used as potential indicators of restless legs syndrome (RLS) in primary care. A total of 351 general practitioners participated in the study. In a first historical patient identification phase, all patients with spontaneous complaints of sleep or leg(More)
BACKGROUND Bronchial asthma is the most frequent chronic childhood disease and can have a marked impact on educational development, activities and quality of life. The AIRMAG survey provides an opportunity to assess asthma and its impact in children in North Africa. OBJECTIVE To describe the prevalence, burden and management of asthma in children in the(More)
BACKGROUND Rotavirus (RV) is the main infectious agent of severe acute gastroenteritis (AGE) in infants and children under 5 years. Given the recent availability of new vaccines, it is important to accurately assess the incidence of rotavirus gastroenteritis (GERV) and their medical and epidemiological consequences. METHODS This work is the French part of(More)
BACKGROUND Reimbursement of the hexavalent vaccine (Infanrix hexa) comprising the DTPa-IPV-Hib components and the hepatitis B valence in a single vaccine was decided in March 2008 in France. The impact of its reimbursement on the hepatitis B vaccine coverage rate was assessed in a study conducted in the general population prior to and after implementation(More)
OBJECTIVE This study presents the development and validation of MIS-A (Medication Intake Survey-Asthma), a new self-report instrument measuring key adherence properties during long-term asthma treatment. DESIGN Within a longitudinal asthma cohort study in France and the United Kingdom, adult patients and caregivers of children responded to(More)