Learn More
Although pioneered by human geneticists as a potential solution to the challenging problem of finding the genetic basis of common human diseases, genome-wide association (GWA) studies have, owing to advances in genotyping and sequencing technology, become an obvious general approach for studying the genetics of natural variation and traits of agricultural(More)
Understanding the genetic bases and modes of adaptation to current climatic conditions is essential to accurately predict responses to future environmental change. We conducted a genome-wide scan to identify climate-adaptive genetic loci and pathways in the plant Arabidopsis thaliana. Amino acid-changing variants were significantly enriched among the loci(More)
Flowering time is a key life-history trait in the plant life cycle. Most studies to unravel the genetics of flowering time in Arabidopsis thaliana have been performed under greenhouse conditions. Here, we describe a study about the genetics of flowering time that differs from previous studies in two important ways: first, we measure flowering time in a more(More)
This paper considers the problem of aggregating several multicast sessions. A multicast session is defined as a subset of clients requiring the same information. Besides, each client can require several multicast sessions. A telecommunication network cannot manage many multicast sessions at the same time. It is hence necessary to group the sessions into a(More)
Although pioneered by human geneticists as a potential solution to the challenging problem of finding the genetic basis of common human diseases 1,2 , advances in genotyp-ing and sequencing technology have made genome-wide association (GWA) studies an obvious general approach for studying the genetics of natural variation and traits of agricultural(More)
Some basic concepts and trends which appear to be essential in the search for biological markers in mental disorders are discussed. Comments related to major psychosis and alcoholism are presented under three headings: (i) heterogeneity of disorders (ii) multifactoriality of disorders and (iii) mental disorders as genetically influenced disorders. Tentative(More)
Autophagy is a catabolic pathway involving the sequestration of cellular contents into a double-membrane vesicle, the autophagosome. Although recent studies have demonstrated that autophagy supports cell migration, the underlying mechanisms remain unknown. Using live-cell imaging, we uncover that autophagy promotes optimal migratory rate and facilitates the(More)
Measuring and controlling the longitudinal phase space and the time-slice emittance of the electron bunch entering at 1.2 GeV in the undulator beam-lines, are crucial to obtain high FEL performances. In the FERMI@Elettra machine, two RF deflecting cavities have been installed at the end of the linac, in order to stretch the electron bunch horizontally and(More)
  • 1