• Publications
  • Influence
Accelerated carcinogenesis following liver regeneration is associated with chronic inflammation-induced double-strand DNA breaks
Hepatocellular carcinoma (HCC) is the third leading cause of cancer mortality worldwide and is considered to be the outcome of chronic liver inflammation. Currently, the main treatment for HCC isExpand
  • 101
  • 2
  • PDF
Hemodynamic response magnetic resonance imaging: application for renal hemodynamic characterization.
BACKGROUND The clinical use of iodinated radiocontrast agents or gadolinium for renal perfusion imaging is limited in the presence of renal dysfunction. We have previously demonstrated theExpand
  • 16
  • 2
  • PDF
Resuscitation With Aged Blood Exacerbates Liver Injury in a Hemorrhagic Rat Model*
Objective:Blood loss and transfusion are frequent among patients undergoing liver surgery. Concerns have been raised about the safety and efficacy of transfusing stored blood. The influence ofExpand
  • 22
Vascular profile characterization of liver tumors by magnetic resonance imaging using hemodynamic response imaging in mice.
Recently, we have demonstrated the feasibility of using hemodynamic response imaging (HRI), a functional magnetic resonance imaging (MRI) method combined with hypercapnia and hyperoxia, forExpand
  • 22
Improved efficacy of a novel anti-angiogenic drug combination (TL-118) against colorectal-cancer liver metastases; MRI monitoring in mice
Background:The poor prognosis of patients with colorectal-cancer liver metastases (CRLM) and the insufficiency of available treatments have raised the need for alternative curative strategies. WeExpand
  • 13
  • PDF
TL-118 and Gemcitabine Drug Combination Display Therapeutic Efficacy in a MYCN Amplified Orthotopic Neuroblastoma Murine Model – Evaluation by MRI
Neuroblastoma (NB) is the most common extra-cranial pediatric solid tumor with up to 50% of NB patients classified as having high-risk disease with poor long-term survival rates. The poor clinicalExpand
  • 4
  • PDF
Assessment of rhabdomyolysis-induced acute kidney injury ( AKI ) in mice using Hemodynamic Response Imaging ( HRI )
Background & Aims: The pathophysiology of rhabdomyolysis-induced acute kidney injury (AKI) is complex and incompletely understood, however hypoxia is one of the factors thought to contribute to renalExpand
  • 1
  • PDF
Improvement of Colorectal Liver Metastases Detection Sensitivity and Specificity by Hemodynamic Response Imaging Combined with a Machine Learning Approach
CRLM (red square); (B,C) The corresponding T1W images obtained before (B) and 66 sec after (C) i.v. injection of Gd-DTPA; The suspected lesion was not enhanced with DCE-MRI (B, enlarged square),Expand
Detection and improvement of anti-angiogenic therapeutic efficacy by using Hemodynamic Response Imaging in mice
Y. Edrei, E. Gross, N. Corchia, E. Dery, S. Ben-Sasson, and R. Abramovitch The Goldyn Savad Inst. for Gene Therapy, Hadassah Hebrew University Medical Center, Jerusalem, Israel, MRI/MRS lab HBRC,Expand