Learn More
PURPOSE The aim of this study was to compare dynamic expiratory imaging and end-expiratory imaging using multi-detector CT (MDCT) of the central airways in patients suspected of tracheobronchomalacia (TBM). METHODS This study had local ethical committee approval. Seventy patients suspected of TBM were prospectively included. All patients underwent(More)
STUDY OBJECTIVES We examined whether psychological variables enable us to predict adherence to CPAP in order to construct a predictive model to identify patients at risk of abandoning treatment. METHOD One hundred and twenty-two Obstructive Sleep Apnoea (OSA) patients were studied before and one month after beginning CPAP treatment. All patients completed(More)
OBJECTIVE Open studies suggest that treatment of obesity hypoventilation syndrome (OHS) by noninvasive ventilation (NIV) restores sleep quality and daytime vigilance and reduces cardiovascular morbidity. However, to our knowledge no randomized controlled trial (RCT) comparing NIV to conservative measures is available in the field. The goal of this study was(More)
PURPOSE This study investigates the effect of increased ocular perfusion pressure (OPP) on optic nerve head (ONH) hemodynamics. METHODS In 21 healthy subjects, the increase in arterial blood pressure (BP), measured continuously using a pneumatic transcutaneous sensor, was produced by isometric exercise consisting of 2 minutes of hand-gripping. ONH blood(More)
BACKGROUND AND OBJECTIVE During continuous positive airway pressure (CPAP) treatment, some patients with obstructive sleep apnoea syndrome (OSAS) require an oronasal mask (ONM) to prevent excessive mouth leakage. Factors contributing to sleep-related mouth opening under CPAP treatment remain known. We compared mouth opening during sleep in patients treated(More)
BACKGROUND Obesity hypoventilation syndrome (OHS) is associated with increased cardiovascular morbidity. What moderate chronic hypoventilation adds to obesity on systemic inflammation and endothelial dysfunction remains unknown. QUESTION To compare inflammatory status and endothelial function in OHS versus eucapnic obese patients. METHODOLOGY 14 OHS and(More)
BACKGROUND Low-grade inflammation may potentially explain the relationship between obstructive sleep apnea syndrome (OSA) and cardiovascular events. However, the respective contribution of intermittent hypoxia and confounders, such as obesity, is still debated. OBJECTIVES To monitor urinary leukotriene E(4) (U-LTE(4)), a validated marker of(More)
CONTEXT Obesity hypoventilation syndrome (OHS) is defined by the association between obesity and daytime arterial hypercapnia. The syndrome includes in variable proportion impaired diaphragmatic weakness, decreased central ventilatory drive and nearly systematically occurrence of sleep apnea. An increased cardio-vascular risk has been demonstrated compared(More)
PURPOSE The aim of this study was to compare intraocular pressure (IOP) measurements using 2 portable tonometers, the Keeler Pulsair Intellipuff and the Reichert PT100, with Goldmann applanation tonometry (GAT). MATERIALS AND METHODS Prospective cross-sectional study was conducted on normotensive and hypertensive patients recruited from the outpatient(More)