Natasha Naumova

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Poly(ADP-ribose) polymerase 1 protein (PARP1) mediates chromatin loosening and activates the transcription of inducible genes, but the mechanism of PARP1 regulation in chromatin is poorly understood. We have found that PARP1 interaction with chromatin is dynamic and that PARP1 is exchanged continuously between chromatin and nucleoplasm, as well as between(More)
The three dimensional structure of the human genome is known to play a critical role in gene function and expression. I used chromosome conformation capture (3C) and 3C-carbon copy (5C) techniques to investigate the three-dimensional structure of the cystic fibrosis transmembrane conductance regulator (CFTR) locus. This is an important disease gene that,(More)
Sociological poll of inhabitants of Chelyabinsk concerning a balanced diet was conducted. Every second chelyabinets needs change of the food, but thus has for this purpose no sufficient money resources. Deficiency in a food of animal protein, the majority of vitamins, macro- and microelements and saturation of a diet by carbohydrates and fats was shown. It(More)
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