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Prephenate dehydrogenase (PD) is one enzyme within the family of TyrA proteins dedicated to the biosynthesis of L-tyrosine (L-Tyr). It catalyzes the NAD+-dependent oxidative decarboxylation of… (More)
A key feature of any living system is the ability to sense and react to the environmental stimuli. The biochemical characterization of the underlying biological sensors combined with advances in… (More)
Interrogation and control of cellular fate and function using optogenetics is providing revolutionary insights into biology. Optogenetic control of cells is achieved by coupling genetically encoded… (More)
Non-canonical amino acids as building blocks for protein biosynthesis facilitate modifications that go far beyond classical genetic engineering. Two complementary techniques allow either… (More)