Natalya M. Shevchenko

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The antiviral activity of different structure fucoidans (α-l-fucans and galactofucans) was studied using two model viral systems based on a lentiviral vectors and a replication competent Moloney murine leukemia virus (Mo-MuLV). It was found that investigated fucoidans have no cytotoxic effects on Jurkat and SC-1cell at the concentration range of 0.001-100(More)
Fucoidan, a sulfated polysaccharide extracted from brown seaweeds, has anticoagulant and antithrombotic activities. Unlike heparine, fucoidan is known to exhibit anticarcinogenic activities. However, the underlying molecular mechanisms of the chemopreventive activities of fucoidan are not understood. Here we report that fucoidan from Laminaria cichorioides(More)
Laminarans and fucoidans from two Russian Far-East (Desmarestia viridis and Dictyota dichotoma) and four Vietnam species (Dictyota divaricata, Padina boryana, Sargassum duplicatum, and S. feldmannii) of brown algae were isolated and studied. Water-soluble polysaccharides from D. divaricata, P. boryana, and S. feldmannii were mainly fucoidans; from D.(More)
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