Natalie Ring

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High-throughput phenotyping is a cornerstone of numerous functional genomics projects. In recent years, imaging screens have become increasingly important in understanding gene-phenotype relationships in studies of cells, tissues and whole organisms. Three-dimensional (3D) imaging has risen to prominence in the field of developmental biology for its ability(More)
A defining feature of Phenoview is its ability to comparatively visualize data for multiple genotype-phenotype combinations simultaneously. This mix-and-match option is suited to investigating the knockout effects of a genotype on multiple traits, and also to the investigation of multiple genotypes that affect the same trait. Selecting the comparative(More)
The International Mouse Phenotyping Consortium (IMPC) is providing the world’s first functional catalogue of a mammalian genome by characterising a knockout mouse strain for every gene. A robust and highly structured informatics platform has been developed to systematically collate, analyse and disseminate the data produced by the IMPC. As the first phase(More)
Although next-generation sequencing has revolutionized the ability to associate variants with human diseases, diagnostic rates and development of new therapies are still limited by a lack of knowledge of the functions and pathobiological mechanisms of most genes. To address this challenge, the International Mouse Phenotyping Consortium is creating a genome-(More)
In the version of this article initially published, it was stated that all transgenic lines were created in the Arabidopsis Col-0 ecotype. However, they were actually generated in the Columbia-Utrecht (Col-utr) ecotype. The error has been corrected in the HTML and PDF versions of the article. In the version of this article initially published, the curves(More)
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