Natalia I. Ivanova

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The appearance of autoimmune thyroiditis in the course of other autoimmune diseases, which do not affect specific organs (systemic lupus erythematosus, Sjögren syndrome, rheumatoid arthritis and others), is more frequent than is usually believed. Nevertheless, it is scarcely studied, especially in children. The purpose of this study was to look for(More)
Under iron-deficient conditions a high-affinity siderophore-mediated iron-transport system is induced in the green alga Scenedesmus incrassatulus R-83. Algal siderophores have a strong avidity for ferric versus ferrous iron, quickly oxidate FeII and efficiently solubilize FeIII hydroxides. The entire ferrated molecule is translocated across the membrane by(More)
The aim of this study was to develop an immunoenzyme method for the determination of anti-AGE antibodies in human serum. Human aortic elastin glycatedin vitro (AGE-elastin) was used as an antigen, expressing AGE-epitopes, common to all glycated proteins. Polyclonal serum from guinea-pig against AGE-Hemocyanin was obtained according to Nakayamaet al.(More)
Freshly-added iron only slightly affected the growth of iron-sufficient cells of the green alga Scenedesmus incrassatulus Bohl, strain R-83, but induced accumulation of malondialdehyde (MDA) in cells and excretion of MDA in the medium. These effects were stronger in response to Fe2+ as compared to Fe3+, but Fe3+ induced the release of more iron-binding(More)
BACKGROUND Red cell distribution width (RDW), neutrophil-lymphocyte ratio (NLR), and platelet count (PLT) routinely tested as part of the complete blood count are indicative of systemic inflammation. The prognostic significance of NLR and PLT in cancer was demonstrated in many studies while the role of RDW has been hardly investigated. The present study(More)
Children with viral respiratory infections and healthy contacts received treatment and prophylaxis with leukocytic interferon. The results emphasize the effectiveness of treatment when interferon is given on the first or second day of the disease. In these cases the course is mild, of short duration, and without complications. Conversely, the clinical(More)
Durch die klinische Etablierung von Algorithmen konnte in den vergangenen Jahren die Qualität der Schockraumversorgung relevant verbessert werden. Regelmäßige Evaluationen und Analysen des Versorgungsprozesses können interdisziplinären Qualitätszirkeln Prozessdaten bereitstellen, um Schwachstellen aufzudecken und die Versorgung weiter zu optimieren. In der(More)
The acute toxicity of the antiulcer drug "Gastrofenzin", synthesized in Bulgaria has been studied in oral, subcutaneous and intravenous application in white rats "Wistar" and white mice "ICR". The main toxicometric parameters (LD50, LD16, LD84 and others) have been determined. The clinical picture of intoxication is characterized mainly by symptoms deriving(More)