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Interconversion of quadruply and quintuply bonded molybdenum complexes by reductive elimination and oxidative addition of dihydrogen.
Transition metal complexes that exhibit multiple metal–metal bonding are of fundamental importance in chemistry. Following decades of intense scrutiny of double, triple, and quadruple metal–metalExpand
Boryl-assisted hydrogenolysis of a nickel-methyl bond.
A stable nickel(II) methyl complex containing a diphosphino-boryl (PBP) pincer ligand is described. Mechanistic studies on the hydrogenolysis of the Ni-Me bond suggest a metal ligand cooperationExpand
Selective reduction of carbon dioxide to bis(silyl)acetal catalyzed by a PBP-supported nickel complex.
The selective reduction of CO2 to the formaldehyde level remains an important challenge and to date only a few catalysts have been developed for this reaction. Herein, we report an efficient catalystExpand
Bimetallic titanocene-gold phosphane complexes inhibit invasion, metastasis, and angiogenesis-associated signaling molecules in renal cancer.
Following promising recent in vitro and in vivo studies of the anticancer efficacies of heterometallic titanocene-gold chemotherapeutic candidates against renal cancer, we report here on theExpand
Experimental and theoretical studies on arene-bridged metal-metal-bonded dimolybdenum complexes.
The bis(hydride) dimolybdenum complex, [Mo2(H)2{HC(N-2,6-iPr2C6H3)2}2(thf)2], 2, which possesses a quadruply bonded Mo2(II) core, undergoes light-induced (365 nm) reductive elimination of H2 andExpand
Preparation of Titanocene–Gold Compounds Based on Highly Active Gold(I)‐N‐Heterocyclic Carbene Anticancer Agents: Preliminary in vitro Studies in Renal and Prostate Cancer Cell Lines
Heterometallic titanocene‐based compounds containing gold(I)‐phosphane fragments have been extremely successful against renal cancer in vitro and in vivo. The exchange of phosphane by N‐heterocyclicExpand
Metal-Dependent DNA Recognition and Cell Internalization of Designed, Basic Peptides
A fragment of the DNA basic region (br) of the GCN4 bZIP transcription factor has been modified to include two His residues at designed i and i+4 positions of its N-terminus. The resulting monomericExpand
Lithium Di- and trimethyl dimolybdenum(II) complexes with Mo-Mo quadruple bonds and bridging methyl groups.
New dimolybdenum complexes of composition [Mo2{μ-Me}2Li(S)}(μ-X)(μ-N^N)2] (3a-3c), where S = THF or Et2O and N^N represents a bidentate aminopyridinate or amidinate ligand that bridges the quadruplyExpand
Trastuzumab gold-conjugates: synthetic approach and in vitro evaluation of anticancer activities in breast cancer cell lines.
We describe the preparation of gold(i)-compounds that are amenable to efficient bioconjugation with monoclonal antibodies via activated ester or maleimide linkers. New Trastuzumab-gold conjugatesExpand
Synthesis and structure of mixed carboxylate-aminopyridinate and -amidinate complexes of dimolybdenum and ditungsten
Abstract We describe in this paper the synthesis and structural characterization of dimolybdenum and ditungsten complexes with M M bonds derived from the metal–metal bonded tetracarboxylatesExpand