Nastasia Nianiaris

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The tumor-specific Grp78 promoter is overexpressed in aggressive tumors. Cancer patients would benefit greatly from application of this promoter in gene therapy and molecular imaging; however, clinical benefit is limited by lack of strategies to target the systemic delivery of Grp78-driven transgenes to tumors. This study aims to assess the systemic(More)
Radiologic examination of patients with severe Graves' disease with possible optic neuropathy has routinely been done with computed tomography (CT). With the more widespread use of magnetic resonance imaging (MRI), its potential use in Graves' disease must be considered. We compared these two imaging techniques for use in severe Graves' orbitopathy.(More)
FEBRUARY 2008 I CATARACT & REFRACTIVE SURGERY TODAY I 19 N anophthalmos is a rare bilateral condition in which the eye is pathologically small but morphologically normal.1 The combination of a short axial length (15 to 20 mm) and a high ratio of lens-to-eye volume results in severe axial hyperopia, a crowded anterior segment, and angle-closure glaucoma.2(More)
The tumor-specificGrp78promoter is overexpressed in aggressive tumors. Cancer patientswould benefit greatly from application of this promoter in gene therapy and molecular imaging; however, clinical benefit is limited by lack of strategies to target the systemic delivery of Grp78-driven transgenes to tumors. This study aims to assess the systemic efficacy(More)
BACKGROUND The authors report a patient with a cryotherapy-induced scleral melt after combined excision and cryotherapy of a conjunctival melanoma arising within primary acquired melanosis with atypia. FINDINGS In a 65-year-old white man, a severe scleral melt developed within 1 month of complete excision of a superficial conjunctival melanoma combined(More)
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