Nassim Douali

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This study aimed to focus on medical knowledge representation and reasoning using the probabilistic and fuzzy influence processes, implemented in the semantic web, for decision support tasks. Bayesian belief networks (BBNs) and fuzzy cognitive maps (FCMs), as dynamic influence graphs, were applied to handle the task of medical knowledge formalization for(More)
Several studies have described the prevalence and severity of diagnostic errors. Diagnostic errors can arise from cognitive, training, educational and other issues. Examples of cognitive issues include flawed reasoning, incomplete knowledge, faulty information gathering or interpretation, and inappropriate use of decision-making heuristics. We describe a(More)
— Doctor usually uses his experience from the clinical practice to confirm a diagnosis and to prescribe an appropriate treatment for a specific patient. The computerized medical reasoning should not only focus on existing medical knowledge but also on physician's previous experiences and new knowledge. Such knowledge and experience are vague and define(More)
Incorrect or improper diagnostic tests uses have important implications for health outcomes and costs. Clinical Decision Support Systems purports to optimize the use of diagnostic tests in clinical practice. The computerized medical reasoning should not only focus on existing medical knowledge but also on physician's previous experiences and new knowledge.(More)
Non-alcoholic fatty liver disease (NAFLD) is a hepatic disease associated with metabolic syndrome. NAFLD covers a spectrum of liver disease from steatosis to non-alcoholic steatohepatitis (NASH) and cirrhosis. NASH is a disease evolving under the influence of various stimuli still poorly understood. In this paper we present new clinical decision support(More)
Personalized medicine may be considered an extension of traditional approaches to understanding and treating diseases, but with greater precision. A profile of a patient's genetic variation can guide the selection of drugs or treatment protocols that minimize harmful side effects or ensure a more successful outcome. In this paper we describe a decision(More)
Clinical guidelines are important means to improve quality of health care while limiting cost and supporting the medical staff. They are written as free text with tables and figures. Transforming them into a formal, computer-processable representation is a difficult task requiring both computer scientist skills and medical knowledge. In this paper the(More)
Personalized medicine is a broad and rapidly advancing field of health care that is informed by each person's unique clinical, genetic, genomic, and environmental information. Health care that embraces personalized medicine is an integrated, coordinated, evidence based approach to individualizing patient care across the continuum. It is very important to(More)
Objective: Non-alcoholic fatty liver disease (NAFLD) is a recently recognized entity related to modern lifestyle and with expanded clinical importance because of the rising incidence of obesity and diabetes. Methods: We have developed a framework for interacting with patient's heterogeneous data (omics, clinical and biological information) and formalizing(More)