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A series of new 3-mercapto-2-methyl-propanoyl-pyrrolidine derivatives (V, VIa-e) were designed. A new validated ACE inhibitors pharmacophore model (hypothesis) was generated for the first time in(More)
A series of novel 2′-tetrazolyl- and 2′-carboxy-biphenylylmethyl-pyrrolidine derivatives (VIIIa–d, IX, X, XIa–d, XII, XIII, XIVa–d, XV ,and XVI) were designed and evaluated as Ang II AT1 receptor(More)