Nasrulla D. Abdullaev

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Early pharmacological studies of Aconitum and Delphinium sp. alkaloids suggested that these neurotoxins act at site 2 of voltage-gated Na(+) channel and allosterically modulate its function. Understanding structural requirements for these compounds to exhibit binding activity at voltage-gated Na(+) channel has been important in various fields. This paper(More)
The new natural flavanones (+)-5,2′-dihydroxy-6,6′,7-trimethoxyflavanone and (+)-5,2′-dihydroxy-6,6′,7,8-tetramethoxyflavanone in addition to the known flavones chrysin, norwogonin, and wogonin were isolated from Scutellaria phyllostachya roots. The structures of the isolated compounds were established using IR, UV and PMR spectra.
Fraxinus raibocarpa Rgl. (Oleaceae) is widely distributed in the flora of Central Asia [1]. The aerial part is used in folk medicine as a relaxant [2] and for cardiovascular diseases [3]. Carbohydrates and the flavonoids kaempferol, astragalin, isoquercitrin, and rutin, were isolated earlier from this plant [4]. We studied the aerial part of F. raibocarpa(More)
Polyprenols from the aerial part of the plant Althaea officinalis were studied. It was shown that polyprenols from leaves were polyprenol homologs with 9–13 isoprene units where undecaprenol dominated. The polyprenol contents in leaves and stems and the component composition of polyprenols of this plant were determined.
More than 20 compounds have been isolated from the bark ofQuercus robur. Monomers: (−)-epicatechin, (−)-epicatechin gallate, (+)-catechin, (+)-catechin gallate, (+)-gallocatechin, (−)-epigallocatechin, and (−)-epigallocatechin gallate; dimeric proanthocyanidins: (+)-catechin-(4α-8)-(+)-catechin, 3-O-galloyl-(+)-catechin-(4α-8)-3-O-galloyl-(+)-catechin,(More)
INTRODUCTION The genus Leonurus L. (fam: Lamiaceae) is represented in Uzbekistan by two species, L. panzerioides Popov. and L. turkestanicus V. I. Krecz. & Kuprian, which are used to treat nervous disorders and also as sedative and hypotensive agents. OBJECTIVES To establish the taxonomic status of Leonurus panzerioides and L. turkestanicus based on their(More)
The new diguaianolide anabsin, C30H40O7, mp 276°C (decomp.), [α]25 +110° (c 1.7; acetone) has been isolated fromArtemisia absinthium L. Anabsin acetate, dehydroanabsin, and dehydroanabsin acetate have been obtained. A comparative study of the1H and13C NMR spectra of anabsin, absinthin, and anabsinthin has been made. The structure of anabsin has been(More)
1. A new germacranolide, which has been called hanphyllin, has been isolated from the epigeal part ofHandelia trichophylla (Schrenk.) Heimerl. 2. On the basis of an analysis of the PMR spectra using the method of multifrequency resonance and a paramagnetic shift reagent — Eu(FOD)3 — the structure of hanphyllin has been established as 3-hydroxy-3α, 6β,(More)