Nasjala Saba Silva

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The aim of this study was to verify whether intracystic injections of alpha-Interferon (IFN-α) in cystic craniopharyngiomas were able to reduce the tumor by activating the Fas apoptotic pathway. Twenty-one patients with cystic craniopharyngiomas treated at the Pediatric Oncology Institute (IOP/GRAACC) of Federal University of São Paulo were submitted to(More)
This study analyzed the intratumoral activity of interferon alpha (IFN-α) in the treatment of cystic craniopharyngiomas. From January 2000 to January 2004, nine patients presenting with cystic craniopharyngiomas were treated with intratumoral injection of IFN-α at the Pediatric Oncology Institute of the Federal University of São Paulo–Escola Paulista de(More)
Taken as proved that brain tumors are the second most frequent childhood neoplasm - only outnumbered by leukemias - we have undertaken a clinical perspective study with seventy brain tumor patients ranging from one to fifteen years of age, throughout a four-year period (1993-1997), based on ambulatory-oriented follow-up. Forty-one male and twenty-nine(More)
Fetal intracranial tumors are rare and their evolution is usually poor. With routine use of antenatal ultrasound imaging, a larger number of such tumors have been diagnosed. During the period from January 1992 to January 2002, 18 cases diagnosed as intracranial tumors in the fetal stage were treated in the Neurosurgery and Obstetrics Departments of the(More)
OBJECTIVES The aim of this study was to verify whether intracystic injections of alpha-Interferon (IFN-alpha) in cystic craniopharyngiomas were able to reduce the tumor by activating the Fas apoptotic pathway. MATERIALS AND METHODS Twenty-one patients with cystic craniopharyngiomas treated at the Pediatric Oncology Institute (IOP/GRAACC) of Federal(More)
9524 Background: Low grade glioma represent 30-40% off all childhood brain tumors. Optimal treatment when feasible is surgical resection resulting in cure in the majority of the cases. However, the management of progressive unresectable low-grade glioma (PULGG) remains controversial. There is increasing evidence that chemotherapy can delay or even allow(More)
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