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objective Oral Candidiasis is the most common HIV related oral lesion. Most patients are infected with a strain originally present as a commensal of the oral cavity. The chronic use of antifungal agents, in the treatment of candidiasis mainly in HIV/AIDS patients leads to the selection of strain resistant to this therapy. The objective of this study was to(More)
BACKGROUND Type-2 diabetes mellitus and its complication are becoming more prevalent in Ethiopia. Evidence abound that the most important predictor of reduction of morbidity and mortality due to diabetes complication is the level of glycemic control achieved. AIMS The aim is to assess adherence to anti diabetic drug therapy and self management practice(More)
BACKGROUND Highly active antiretroviral therapy (HAART) has markedly decreased the morbidity and mortality due to HIV disease. However, toxicities, comorbidity, pregnancy, and treatment failure, among others, would result in frequent initial HAART regimen change. AIM The study was designed to assess the causes of initial highly active antiretroviral(More)
AIM: Medicinal plants are integral source of easily available remedy used in rural healthcare system. The aim of the study was to document available medicinal plants, methods of preparation and major uses in Southeast Ethiopia. METHODS: An ethnobotanical survey was conducted in Bale Zone, Southeastern Ethiopia. A structured questionnaire was used to collect(More)
INTRODUCTION Treat-to-target (T2T) strategies using a protocol of pre-defined adjustments of disease-modifying anti-rheumatic drugs (DMARDs) according to disease activity improve outcomes for patients with rheumatoid arthritis (RA). However, successful implementation may be limited by deviations from the protocol. The aim of this study was to determine the(More)
Medication adherence is believed to be a major contributor to treatment outcomes yet studies quantifying this relationship as rare in rheumatoid arthritis (RA). To determine the association of adherence to DMARD therapy with treatment outcomes among new and existing DMARD users over 2 years. Relevant clinical parameters were obtained from a longitudinal(More)
OBJECTIVE To determine the minimum cut-points for rate of physician compliance with a treat-to-target (T2T) strategy needed to achieve optimal rates of remission or low disease activity (LDA). METHOD In this analysis of longitudinal observational data from patients with early RA, physician compliance with a T2T treatment protocol was determined for each(More)
Development of the treat-to-target (T2T) strategy, the process whereby drug therapy is adjusted until the therapeutic goal is achieved, has revolutionized how rheumatoid arthritis (RA) patients are treated. With the advent of T2T, the management of RA is more effective than ever, with the possibility of remission and other favorable clinical and(More)
OBJECTIVE To investigate the association between adherence to treat-to-target (T2T) protocol and disease activity, functional outcomes, and radiographic outcomes in early rheumatoid arthritis (RA). METHODS Data from a longitudinal cohort of patients with early RA were used. Adherence was determined at each followup visit over 3 years according to(More)
The objective of the study was to assessing patterns of drug use by using World Health Organization prescribing, patient care and health facility indicators in Southwest Ethiopia. A cross sectional study was carried out in four randomly selected health facilities. Retrospectively the prescription papers analyzed according to WHO guideline. Prospectively 35(More)