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Over the past decade, dramatic increases in computational power and improvement in image analysis algorithms have allowed the development of powerful computer-assisted analytical approaches to radiological data. With the recent advent of whole slide digital scanners, tissue histopathology slides can now be digitized and stored in digital image form.(More)
Diagnosis of recurrent miscarriage due to abnormally high number of uterine natural killer (uNK) cells has recently been made possible by a protocol devised by Quenby et al. Hum Reprod 2009;24(1):45-54. The diagnosis involves detection and counting of stromal and uNK cell nuclei in endometrial biopsy slides immunohistochemically stained with haematoxylin(More)
The inherent complexity and non-homogeneity of texture makes classification in medical image analysis a challenging task. In this paper, we propose a combined approach for meningioma subtype classification using subband texture (macro) features and micro-texture features. These are captured using the Adaptive Wavelet Packet Transform (ADWPT) and Local(More)
Computer aided diagnosis (CAD) is aimed at supporting the pathologists in their diagnosis. In this paper, we present an algorithm for texture-based classification of colon tissue patterns. In this method, a single band is selected from its hy-perspectral cube and spatial analysis is performed using circular local binary pattern (CLBP) features. A novel(More)
We present a novel texture classification algorithm using 2-D discrete wavelet transform (DWT) and support vector machines (SVM). The DWT is used to generate feature images from individual wavelet subbands, and a local energy function is computed corresponding to each pixel of the feature images. This feature vector is first used for training and later on(More)
Diagnosis and cure of colon cancer can be improved by efficiently classifying the colon tissue cells from biopsy slides into normal and malignant classes. This paper presents the classification of hyperspectral colon tissue cells using morphology of gland nuclei of cells. The application of hyper-spectral imaging techniques in medical image analysis is a(More)
—Histopathology diagnosis is based on visual examination of the morphology of histological sections under a microscope. With the increasing popularity of digital slide scanners, decision support systems based on the analysis of digital pathology images are in high demand. However, computerised decision support systems are fraught with problems that stem(More)
In this paper, we present a stochastic model for glandular structures in histology images of tissue slides stained with Hematoxylin and Eosin, choosing colon tissue as an example. The proposed Random Polygons Model (RPM) treats each glandular structure in an image as a polygon made of a random number of vertices, where the vertices represent approximate(More)
Colorectal adenocarcinoma originating in intestinal glandular structures is the most common form of colon cancer. In clinical practice, the morphology of intestinal glands, including architectural appearance and glandular formation, is used by pathologists to inform prognosis and plan the treatment of individual patients. However, achieving good(More)
Motivated by the fact that in images, there is usually a presence of local strongly oriented harmonics, a representation which is both well-localised in frequency and orientation is desirable to efficiently describe such oriented harmonic features. Here we introduce a family of multiscale trigonometric bases for a bi-variate function called the multiscale(More)