Naser A. Ghaleb

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The distribution of atrial natriuretic peptide (ANP) in blood plasma and cardiac muscle and its effects on ventricular myocyte contraction and intracellular free calcium concentration [Ca2+]i in the streptozotocin (STZ)-induced diabetic rat have been investigated. Blood plasma concentration and heart atrial and ventricular contents of ANP were significantly(More)
The polycycles 2-(piperidinyl methanamide)-5-(3',4'-methylenedioxyphenyl)-8-aryl -7,9-dioxo-8-aza bicyclo[4.3.0]non-3-ene 5a-f were synthesized via Diels-Alder cycloaddition reaction of piperine 1 with N-arylmaleimides 4a-f, or with maleic anhydride 2, followed by reaction of the product 3 with amino benzene derivatives (ArNH2). Some of the synthesized(More)
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