Naren Raja

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A study of the conjugal transfer of ColV,I-K94 tn 10 from acid-treated donors suggested that acid-habituated recipients repair acid-damaged plasmid DNA better than those that are not habituated. The presence of an increased repair activity for acid-damaged DNA in habituated cells was confirmed by isolating pBR322 from acid-treated organisms; habituated(More)
Induction of acid resistance (habituation) in Escherichia coli at pH 5.0 took ca 5 min in broth at 37 degrees C and 30-60 min in minimal medium. Induction occurred at a range of pH values from 4.0 to 6.0; it was dependent on continuing protein and RNA synthesis but substantial acid resistance appeared in the presence of nalidixic acid. Acid resistance was(More)
In the present investigations, the preventive effect of Vitamin B12 was evaluated against cyclophosphamide induced cytogenetic analysis in the mouse bone marrow cells. The single ip administration of Vitamin B12 at the dose of 125, 250 and 375 mg/kg body weight, 24 hours prior the administration of cyclophosphamide (at the dose of 50 mg/kg) have(More)
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