Naoko Tomita

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We identified a thymosin-beta4 gene overexpression in malignant mouse fibrosarcoma cells (QRsP-30) that were derived from clonal weakly tumorigenic and nonmetastatic QR-32 cells by using a differential display method. Thymosin-beta4 is known as a 4.9-kd polypeptide that interacts with G-actin and functions as a major actin-sequestering protein in cells. All(More)
We have derived theoretical equations describing the adsorption of carcinogen to gels in an immersion medium containing carcinogens. The theory was developed for a cylindrical boundary condition under the assumption of a carcinogen diffusion-limited process combined with the "moving boundary picture (Furusawa et al., 2007)". The time course of the adsorbed(More)
Japan promotes research related to intractable diseases and financially supports patients with these diseases. Intractable diseases are designated as those that fulfill the following criteria: (1) rarity (affecting less than 0.1% of the population in Japan), (2) unknown etiology, (3) lack of effective treatment, (4) necessity of long-term treatment, and (5)(More)
Introduction of Electronic Medical Record (EMR) into a hospital was started from 1999 in Japan. Then, most of all EMR company said that EMR improved efficacy of the management of the hospital. National Hospital Organization (NHO) has been promoting the project and introduced EMR since 2004. NHO has 143 hospitals, 51 hospitals offer acute-phase medical care(More)
To control the dynamics of dialysis-induced anisotropic gel formation, we have derived a theoretical expression for the development of the gel layer for a simple case where no cross-link sites for cross-linking agents exists and the inflow and the outflow of low molecular weight components through the dialysis membrane modify the state of polymer molecules(More)
407 In most regions, over the past 50 years, socioeconomic development has been accompanied by large falls in fertility and equally dramatic increases in life expectancy.1 This phenomenon has led to rapidly ageing populations around the world. The fastest change is occurring in lowandmiddle-income countries. Even in subSaharan Africa, which has the world’s(More)
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