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OBJECTIVE We sought to analyze the postoperative hospital mortality and postoperative neurologic dysfunction in patients who had total arch replacement for atherosclerotic arch aneurysms using our recent refined technique. METHODS Between June 1997 and April 2000, 50 consecutive patients underwent total arch replacement with an aortic arch branched graft(More)
BACKGROUND To evaluate the results of antegrade selective cerebral perfusion as a method of brain protection during surgery of the thoracic aorta and to determine predictors of hospital mortality and adverse neurologic outcome. METHODS Between October 1995 and March 2002, 588 patients underwent aortic surgery with the aid of antegrade selective cerebral(More)
BACKGROUND We report our clinical experience with total arch replacement using aortic arch branched graft in an attempt to determine the independent predictors of both in-hospital mortality and neurologic outcome. METHODS We studied 220 consecutive patients who underwent total arch replacement using aortic arch branched graft between May 1990 and June(More)
BACKGROUND Redissection of the aortic root after supracommissural aortic graft replacement with reapproximation of the layers of the dissected aortic root is relatively rare. Causes and surgical treatment of this lesion remain controversial. METHODS From January 1983 to September 2000, 130 patients had emergency operation for acute type A aortic(More)
BACKGROUND The aim of this study was to assess the risk factors for the early and late outcome of the surgical treatment of acute type A aortic dissection. METHODS From 1983 to 2000, a total of 130 patients underwent operation for acute type A aortic dissection. Extent of distal aortic resection included ascending aorta in 19 patients (15%), hemiarch in(More)
BACKGROUND The present study was conducted to report our clinical experience with aortic arch replacement using selective cerebral perfusion (SCP) and determine the independent predictors of in-hospital mortality and neurologic outcome. METHODS We studied 472 consecutive patients who underwent aortic arch replacement using SCP between January 1986 and(More)
BACKGROUND To evaluate the impact of an aggressive surgical approach on early and late outcome in type A aortic dissection. METHODS From 1983 to 2001, 240 patients underwent operation for acute (n = 138) and chronic (n = 102) type A aortic dissection. The extent of distal aortic resection included the ascending aorta in 39 (16%) patients, hemiarch (HAR)(More)
BACKGROUND Prophylactic transplantation of marrow stromal cells (MSCs) before spinal cord ischemia has been shown to attenuate neurologic injures. We sought to investigate the therapeutic effect of MSCs on ischemia-injured spinal cord. METHODS Marrow stromal cells were expanded in vitro and prelabeled with bromodeoxyuridine. Spinal cord ischemia was(More)
OBJECTIVE We sought to report the clinical experience with extended total arch replacement for acute type A aortic dissection and to determine the factors that influence early mortality, late survival, and late reoperation. METHODS Between December 1988 and August 1998, 70 patients underwent emergency graft replacement of both the ascending aorta and the(More)
OBJECTIVE Reactive free radical species are thought to be involved in ischemic spinal cord injury. We investigated the effects of edaravone (Mitsubishi Pharma Co, Tokyo, Japan), a free radical scavenger, on spinal ischemia-reperfusion injury in a rabbit model. We also sought to estimate free radicals in the spinal cord using the microdialysis method. (More)