Naoki Moriyama

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Atrial natriuretic peptide (ANP) contributes to the inhibition of such causes of inflammation as the lipopolysaccharide (LPS)-induced productions of nitric oxide (NO) and proinflammatory cytokines [including interleukin-1 (IL-1)] in macrophages. In the present study we used primary cultures of rat brain macrophage-like cells (i.e., microglial cells) to(More)
We investigated whether angiotensin (ANG) II and its receptors contribute to lipopolysaccharide (LPS)-induced microglial activation through activation of the proinflammatory transcription factors nuclear factor kappaB (NF-kappaB) and activator protein-1 (AP-1). Using primary microglial cell cultures, we examined whether losartan [ANG type 1 receptor (AT(1))(More)
A recent report demonstrated that t(8;16) (p11;p13) may be linked to acute monocytic leukaemia (AMoL) of differentiated subtype (M5b) with active haemophagocytosis by leukaemic cells. Only two cases of neonatal AMoL with t(8;16)(p11;p13) have been reported; M5b with haemophogocytosis and M5a. We report a case of neonatal AMoL (M5b) with t(8;16)(p11;p13),(More)
Polymyxin B, a cyclic cationic polypeptide antibiotic, binds to the lipid A of bacterial endotoxin (lipopolysaccharide; LPS) to inhibit LPS-induced fever. On the basis of a casual observation, we hypothesised that in rats (unlike in rabbits and goats), intravenous (i.v.) polymyxin B would decrease resting body temperature. A single i.v. injection of(More)
A 64-year-old woman (151 cm, 43 kg) with well controlled hypertension was diagnosed as having right lung cancer at S8 segment. She underwent right S8 segmentectomy by video assisted thoracic surgery (VATS) under general anesthesia combined with epidural anesthesia. Her vital signs were stable and BIS value was around 45 before the surgeon injected the air(More)
An elderly woman suddenly had a right side cerebral air embolism (CAE) with seizures and unconsciousness during bronchoscopic biopsies, so was transferred to our hospital. Magnetic resonance imaging (MRI) showed no acute ischemic changes two hours after CAE in both hemispheres. Despite no active MRI findings, near-infrared spectroscope (NIRS), started soon(More)
We report a child with relapsed acute lymphocytic leukaemia in whom cytoplasmic granules were present in the leukaemic cells of the cerebrospinal fluid (CSF) but not in those of the bone marrow (BM). The leukaemic cells of the BM were of B-cell lineage whereas those of the CSF had both B-cell and myeloid antigens.
Novel PdO/La10Si6-xCoxO27-δ/γ-Al2O3 catalysts with applications to methane combustion were developed. These materials were based on the use of La10Si6-xCoxO27-δ as a promoter, because this compound has an oxide ion conducting apatite-type structure that allows the smooth migration of active oxygen to the PdO activator. Co3+/2+ ions were also introduced into(More)