Naoki Horimoto

Learn More
To evaluate whether mouthing movement in the human fetus is related to advance in gestational age and whether such movement is concurrent with rapid eye movement or non-rapid eye movement phases, 26 fetuses from 28 to 41 weeks' gestation were observed for 60 continuous minutes with real-time ultrasonography. It was evident that regular mouthing movement(More)
We tested whether a chimpanzee fetus could form an association between an extrauterine tone and vibroacoustic stimulation (VAS) using classical conditioning treatment. Two kinds of pure tone were used as the conditioned stimuli, one where a 500-Hz tone was always followed by a VAS of 80 Hz (110 gal), the unconditioned stimulus (US), and another where a(More)
Fetal behavioural patterns were examined to test whether they could be used to localise sites of brain damage antenatally. Decreased fetal movement, persistent nonreactive fetal heart rate (FHR) pattern, and/or central nervous system malformation were used as indicators of possible neurological impairment. Ten fetuses tested in this way underwent further(More)
The goal of this study was to determine whether rapid eye movement and slow eye movement exist during the eye-movement period in the human fetus in utero. We studied 21 fetuses with real-time ultrasonography, 10 from 33 to 36 weeks and 11 from 37 to 41 weeks' gestation. We used the duration of eye-movement unit as a parameter and calculated the cumulative(More)
To elucidate diurnal variations in eye movement and fetal heart rate (FHR) variability in the term fetus, we observed these two parameters continuously for 24 h, using real-time ultrasound and Doppler cardiotocograph, respectively. Studied were five uncomplicated fetuses at term. The time series data of the presence and absence of eye movement and mean FHR(More)
OBJECTIVE Our purpose was to characterize eye movement patterns in the human fetus at term persisting in breech presentation. STUDY DESIGN Studied were 11 fetuses in breech presentation and 12 in cephalic presentation at 36 to 41 weeks' gestation, of which the presentation remained unchanged from 32 weeks' gestation until delivery. With real-time(More)
We describe three fetuses at term that demonstrated abnormal behavioral patterns in utero when observed using real-time ultrasound. The abnormal patterns turned out to have neurologic correlations after birth. In case 1, despite a normal breathing pattern, no movement in any of the four extremities was observed, thus suggesting the existence of a spinal(More)
Since 1981, when eye movements of the human fetus were first reported, the study of fetal eye movements has increased, mainly focusing on the ontogenesis of eye movements and as one parameter of behavioral states. Using real-time ultrasound, fetal eye movements can be clearly observed from 14 weeks of gestational age. Fetal eye movements may be described in(More)
The objective of this study was to investigate whether micturition occurs, temporally related to the onset of the rapid eye movement (REM) period, in the human fetus. The study was made on 139 fetuses at 33-36 weeks and 153 at 37-41 weeks gestation. The discrepancies between the expected (F(exp)) and observed (F(obs)) frequencies of time lag between the(More)
In order to reveal whether or not brain impairment occurs in the human fetus during the intrauterine period, we described three term fetuses, having successful prenatal diagnosis of localized brain lesion, through the real-time ultrasound observation of in utero behavioral patterns. Movement of extremities, breathing movement, alternation of REM (rapid eye(More)