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BACKGROUND There are few data on empiric, stepped therapy for heartburn relief or subsequent relapse in primary care. AIMS To compare heartburn relief produced by a proton pump inhibitor-start or an H(2)-receptor antagonist-start with step-up therapy, as needed, followed by a treatment-free period to assess relapse. METHODS Heartburn-dominant(More)
BACKGROUND Laser speckle flowgraphy (LSFG) enables noninvasive quantification of the retinal circulation in glaucoma patients. In this study, we tested the intrasession reproducibility of LSFG-NAVI, a modified LSFG technique. METHODS Sixty-five eyes from 33 subjects (male (M):female (F) = 17:16) with a mean age of 49.4 ± 11.2 years were examined in this(More)
SUMMARY We propose an automatic image mosaicing method which can construct a panoramic image from a collection of digital still images. Our method is fast and robust enough to process a nonplanar scene with unrestricted camera motion. The method includes the following two techniques. First, we use a multiresolution patch-based optical flow estimation for(More)
BACKGROUND Gastroesophageal reflux disease (GERD) is the most prevalent acid-related disorder in Canada and is associated with significant impairment of health-related quality of life. Since the last Canadian Consensus Conference in 1996, GERD management has evolved substantially. OBJECTIVE To develop up-to-date evidence-based recommendations relevant to(More)
We propose an automatic line tracking method which can deal with broken or closely-spaced line segments more accurately than previous methods over an image sequence. The method uses both grey scale information of the original images and geometric attributes of line segments. By using our hierarchical optical ow technique, we can get a good prediction of(More)
Objective To determine whether a " test for Helicobacter pylori and treat " strategy improves symptoms in patients with uninvestigated dyspepsia in primary care. Design Randomised placebo controlled trial. Setting 36 family practices in Canada. Participants 294 patients positive for H pylori (13 C-urea breath test) with symptoms of dyspepsia of at least(More)
The Kyoto global consensus report on Helicobacter pylori (H. pylori) gastritis has had a great effect on the field of H. pylori studies worldwide. For the first time H. pylori gastritis was defined entirely as an infectious disease and H. pylori-associated dyspepsia as a new category of organic dyspepsia apart from functional dyspepsia, together with a(More)
BACKGROUND Eyes with glaucoma are characterized by optic neuropathy with visual field defects in the areas corresponding to the optic disk damage. The exact cause for the glaucomatous optic neuropathy has not been determined. Myopia has been shown to be a risk factor for glaucoma. The purpose of this study was to determine whether a significant correlation(More)
BACKGROUND The purpose of this study was to investigate the correlations between microcirculation in the optic disc, average peripapillary retinal nerve fiber layer thickness cupping parameters, and visual field defects in glaucoma patients with the generalized enlargement disc type. METHODS A total of 38 eyes from 38 glaucoma patients with the(More)
BACKGROUND Gastro-esophageal reflux disease (GERD) is a common disease. It impairs health related quality of life (HRQL). However, the impact on utility scores and work productivity in patients with moderate to severe GERD is not well known. METHODS We analyzed data from 217 patients with moderate to severe GERD (mean age 50, SD 13.7) across 17 Canadian(More)